Genetic predisposition
A genetic predisposition (sometimes also called genetic susceptibility) is an increased likelihood of developing a particular disease based on a person's genetic makeup. A genetic predisposition results from specific genetic variations that are often inherited from a parent. These genetic changes contribute to the development of a disease but do not directly cause it. Some people with a predisposing genetic variation will never get the disease while others will, even within the same family. (MedlinePlus, May 14, 2021)
Contributing factors can be any number of things, including:
a) Other genes;Acute illnesses, like those caused by a virus or bacterium;
Environmental exposures, like pollution or pesticides;
b) Smoking or other tobacco use
Alcohol or drug abuse; Hormonal changes, such as having a baby or going through menopause;
c) Surgery; Long-term sleep deprivation. (Dellwo, A., May 06., 2024)
MedlinePlus, (May 14, 2021) What does it mean to have a genetic predisposition to a disease? Retrieved from: https://bit.ly/3EeM3v6
Dellwo, A..,( May 06, 2024). Verywell mind. What Is Genetic Predisposition? Genetic Predisposition and What It Means Understanding Multifactoral Illness and Predisposition. https://www.verywellhealth.com/genetic-predisposition-5087879